Open AccessPrediction of Treatment Response and Survival with Chemotherapy for Metastatic Penile Cancer by the Modified Glasgow Prognostic Score
Author(s) -
Desiree-Louise Draeger,
Sophie Groh,
Tim Buchholz,
Maria Woehl,
Julia Nolting,
Oliver W. Hakenberg
Publication year - 2021
Publication title -
urologia internationalis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.771
H-Index - 53
eISSN - 1423-0399
pISSN - 0042-1138
DOI - 10.1159/000519358
Subject(s) - medicine , chemotherapy , proportional hazards model , univariate analysis , c reactive protein , gastroenterology , cancer , oncology , multivariate analysis , inflammation
There is increasing evidence that a persistent systemic inflammatory response predicts lower survival in patients with malignant disease. The modified Glasgow Prognostic Score (mGPS) is defined by a combination of elevated C-reactive protein (CRP) (>10 mg/L) and hypoalbuminemia (<35 g/L). It is considered as an independent prognostic marker in several organ malignancies. The aim of this study was to investigate the value of mGPS in metastatic penile carcinoma in predicting treatment response and survival.