Open AccessBiomarker-Based Management of AKI: Fact or Fantasy?
Author(s) -
Marlies Ostermann,
Emma Karsten,
Nuttha Lumlertgul
Publication year - 2021
Publication title -
the nephron journals/nephron journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 72
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000518365
Subject(s) - medicine , acute kidney injury , biomarker , intensive care medicine , renal function , kidney disease , etiology , chemistry , biochemistry
New biomarkers for acute kidney injury (AKI) have improved our understanding of the etiology and pathogenesis of AKI. Depending on their origin, function, and kinetic profile, biomarkers have a role in screening, diagnosis, prognostication, and monitoring of AKI. This offers opportunities to improve the management of AKI, but concerns and limitations remain. In this review, we summarize the current role of new AKI biomarkers in the management of AKI and outline some of the ongoing limitations and challenges.