Open AccessNeuroimmune Circuits Activated by Vagus Nerve Stimulation
Author(s) -
S. Kuwabara,
Eibhlin Goggins,
Shinji Tanaka
Publication year - 2021
Publication title -
the nephron journals/nephron journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 72
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000518176
Subject(s) - vagus nerve stimulation , medicine , inflammation , vagus nerve , neuroscience , stimulation , immune system , immunology , biology
The interaction between the nervous system and the immune system has recently been well-recognized. Vagus nerve stimulation (VNS) presents potential as an anti-inflammatory therapy through activation of neuroimmune pathways. Detailed understanding of the neuroimmune pathways VNS evokes is critical in order to successfully use it in the clinic for the treatment of acute kidney injury, in which inflammation plays an important role. In this review, we describe recent findings regarding VNS-induced neuroimmune pathways responsible for anti-inflammation and tissue protection.