Open AccessAcute Kidney Injury in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention: Pathophysiologies, Risk Factors, and Preventive Measures
Author(s) -
Yafeng Zhang,
Dadong Liu,
Yue Zhou,
Ji-Zhuang Lou
Publication year - 2021
Publication title -
cardiology
Language(s) - English
Resource type - Journals
eISSN - 1421-9751
pISSN - 0008-6312
DOI - 10.1159/000517991
Subject(s) - medicine , conventional pci , percutaneous coronary intervention , acute kidney injury , acute coronary syndrome , contrast induced nephropathy , cardiology , context (archaeology) , perioperative , renal function , intensive care medicine , surgery , myocardial infarction , paleontology , biology
Background: Percutaneous coronary intervention (PCI) has been an effective treatment for acute coronary syndrome (ACS) patients. Acute kidney injury (AKI) is one of the common complications after PCI, which seriously affects the living quality and survival time of patients. The approach followed for the patient with AKI after PCI depends on the clinical context and may vary by resource availability. Summary: This review focuses on the pathophysiologies, influencing factors, and preventive measures of AKI in patients with ACS after PCI. The knowledge may better serve the patients and improve their outcomes. Key Messages: Many studies have been carried out for the definition and standard of AKI in the past few years. Etiologies of AKI after PCI included renal damage of contrast medium and atherosclerotic embolism, cardiac insufficiency and surgical factors on renal function. Basic conditions, treatment modalities, and perioperative changes are major risk factors of AKI. Studies have reported that the prevention of contrast-induced nephropathy, modulating the volume overload, some pharmaceuticals and blood purification treatment are helpful to prevent the occurrence of AKI.