Open AccessThe Role of Obesity in Predicting the Clinical Outcomes of COVID-19
Author(s) -
Sahin Serdar,
Sezer Havva,
Cicek Ebru,
Yagız Ozogul Yeliz,
Yildirim Murat,
Icli Tevhide Betul,
Polat Korkmaz Ozge,
Durcan Emre,
Sulu Cem,
Somay Kayra,
Bekdemir Bahar,
Borekci Sermin,
Yazici Dilek,
Deyneli Oguzhan,
Ergonul Onder,
Tabak Fehmi,
Dikmen Yalim,
Ozkaya Hande Mefkure,
Gonen Mustafa Sait,
Damci Taner,
Ilkova Hasan,
Yumuk Volkan Demirhan
Publication year - 2021
Publication title -
obesity facts
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.398
H-Index - 45
eISSN - 1662-4033
pISSN - 1662-4025
DOI - 10.1159/000517180
Subject(s) - research article
The aim of this was to describe the predictors of mortality related to COVID-19 infection and to evaluate the association between overweight, obesity, and clinical outcomes of COVID-19. Methods: We included the patients >18 years of age, with at least one positive SARS-CoV-2 reverse transcriptase-polymerase chain reaction. Patients were grouped according to body mass index values as normal weight <25 kg/m2 (Group A), overweight from 25 to <30 kg/m2 (Group B), Class I obesity 30 to <35 kg/m2 (Group C), and ≥35 kg/m2 (Group D). Mortality, clinical outcomes, laboratory parameters, and comorbidities were compared among 4 groups. Results: There was no significant difference among study groups in terms of mortality. Noninvasive mechanical ventilation requirement was higher in group B and D than group A, while it was higher in Group D than Group C (Group B vs. Group A [ p = 0.017], Group D vs. Group A [ p = 0.001], and Group D vs. Group C [ p = 0.016]). Lung involvement was less common in Group A, and presence of hypoxia was more common in Group D (Group B vs. Group A [ p = 0.025], Group D vs. Group A [ p < 0.001], Group D vs. Group B [ p = 0.006], and Group D vs. Group C [ p = 0.014]). The hospitalization rate was lower in Group A than in the other groups; in addition, patients in Group D have the highest rate of hospitalization (Group B vs. Group A [ p < 0.001], Group C vs. Group A [ p < 0.001], Group D vs. Group A [ p < 0.001], Group D vs. Group B [ p < 0.001], and Group D vs. Group C [ p = 0.010]). Conclusion: COVID-19 patients with overweight and obesity presented with more severe clinical findings. Health-care providers should take into account that people living with overweight and obesity are at higher risk for COVID-19 and its complications.