Open AccessNeuropsychological Equivalence of the Clinical Diagnosis of Mild Cognitive Impairment in the National Alzheimer’s Coordinating Center Uniform Data Set and Alzheimer’s Disease Neuroimaging Initiative
Author(s) -
Andrew M. Kiselica,
Jared F. Benge,
Alzheimer’s Disease Neuroimaging Initiative
Publication year - 2021
Publication title -
dementia and geriatric cognitive disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.026
H-Index - 110
eISSN - 1421-9824
pISSN - 1420-8008
DOI - 10.1159/000516413
Subject(s) - alzheimer's disease neuroimaging initiative , neuropsychology , cohort , neuroimaging , dementia , psychology , alzheimer's disease , cognition , clinical psychology , disease , cognitive impairment , medicine , psychiatry
Our understanding of Alzheimer's disease may be improved by harmonizing data from large cohort studies of older adults. Differences in the way clinical conditions, like mild cognitive impairment (MCI), are diagnosed may lead to variability among participants that share the same diagnostic label. This variability presents a challenge for cohort harmonization and may lead to inconsistency in research findings. Little research to date has explored the equivalence of the diagnostic label of MCI across 2 of the largest and most influential cohort studies in the USA: the National Alzheimer's Coordinating Center (NACC) and the Alzheimer's Disease Neuroimaging Initiative (ADNI).