Open AccessCold Agglutinin-Mediated Autoimmune Hemolytic Anemia in Association with Antiphospholipid Syndrome
Author(s) -
Ram Gelman,
Fadi Kharouf,
Yuval Ishay,
Alexander Gural
Publication year - 2021
Publication title -
acta haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 56
eISSN - 1421-9662
pISSN - 0001-5792
DOI - 10.1159/000516295
Subject(s) - autoimmune hemolytic anemia , cold agglutinin disease , antiphospholipid syndrome , immunology , hemolytic anemia , medicine , cold agglutinin , complement system , evans syndrome , immune system , antibody
Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them. Herein, we report a unique case of cold agglutinin hemolytic anemia in a patient with a known primary antiphospholipid syndrome.