Open AccessAdalimumab in the Management of Isotretinoin-Induced Acne Fulminans: Report of a Case
Author(s) -
Claudio Marasca,
Gabriella Fabbrocini,
Luisa Abategiovanni,
Elisa Camela,
Mariateresa Nocerino,
Adriana Di Guida,
Gaia De Fata Salvatores
Publication year - 2021
Publication title -
skin appendage disorders
Language(s) - English
Resource type - Journals
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000512032
Subject(s) - isotretinoin , medicine , acne , adalimumab , dermatology , disease
Acne fulminans (AF) is a rare, acute, and severe form of acne vulgaris often associated with systemic symptoms. Its treatment is challenging and controversial. We report a case of isotretinoin-induced AF (IIAF) in a 12-year-old boy resistant to traditional therapies (oral steroids and isotretinoin). The patient was successfully treated with adalimumab that can be considered an effective off-label option in the treatment of resistant IIAF in children.