Angiolipoma: A Unique Cause of Carpal Tunnel Syndrome

Carpal tunnel syndrome is one of the most common conditions affecting the hand. The majority of cases are idiopathic, with tumours causing less than 3% of cases. We present a unique case of an angiolipoma overlying the carpal tunnel as a cause of median nerve compression. A 54-year-old female presented with signs and symptoms consistent with carpal tunnel syndrome associated with an enlarging lump overlying the carpal tunnel on the palmar surface of her hand. Nerve conduction studies confirmed median neuropathy. The case was successfully treated by surgical excision of the tumour and open carpal tunnel release. Histopathology confirmed the presence of an angiolipoma. The patient had complete resolution of symptoms at the final 6-week follow-up. This case highlights the importance of considering tumours in the differential diagnosis of carpal tunnel syndrome.