The Effect of Kidney Biopsy on Glomerular Filtration Rate: A Frequent Patient Concern | Zendy

Rakesh Dattani | Zendy; Richard Corbett | Zendy; Jack Galliford | Zendy; Peter Hill | Zendy; Tom Cairns | Zendy; H. Terence Cook | Zendy; Candice Roufosse | Zendy; Damien Ashby | Zendy

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The Effect of Kidney Biopsy on Glomerular Filtration Rate: A Frequent Patient Concern

Author(s) -

Rakesh Dattani,

Richard Corbett,

Jack Galliford,

Peter Hill,

Tom Cairns,

H. Terence Cook,

Candice Roufosse,

Damien Ashby

Publication year - 2020

Publication title -

american journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 85

eISSN - 1421-9670

pISSN - 0250-8095

DOI - 10.1159/000511798

Subject(s) - medicine , renal function , biopsy , renal biopsy , urology , kidney , retrospective cohort study , kidney disease , confidence interval , percutaneous , surgery

The effect of percutaneous kidney biopsy on glomerular filtration rate has never been identified, though it is frequently a concern raised by patients. Following a clinical interaction with an inquisitive patient undergoing her fifth biopsy, we attempted to estimate the effect using retrospective data. In a cohort of patients with stable kidney function undergoing transplant biopsy without clinical indication (as part of a surveillance programme) the effect of biopsy was observed as a step change in glomerular filtration rate. Reassuringly, the loss of glomerular filtration rate resulting from a biopsy, has a 1-sided 95% confidence interval of <1.4 mL/min.

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