Open AccessShort- and Long-Term Outcomes of Simultaneous Hepatic Artery Resection and Reconstruction for Perihilar Cholangiocarcinoma
Author(s) -
Shindo Yoshitaro,
Kobayashi Shogo,
Wada Hiroshi,
Tokumitsu Yukio,
Matsukuma Satoshi,
Matsui Hiroto,
Nakajima Masao,
Yoshida Shin,
Iida Michihisa,
Suzuki Nobuaki,
Takeda Shigeru,
Hoshii Yoshinobu,
Eguchi Hidetoshi,
Nagano Hiroaki
Publication year - 2020
Publication title -
gastrointestinal tumors
Language(s) - English
Resource type - Journals
eISSN - 2296-3766
pISSN - 2296-3774
DOI - 10.1159/000511164
Subject(s) - research article
Because surgical resection with simultaneous hepatic artery (HA) resection and reconstruction for perihilar cholangiocarcinoma (PHC) is technically demanding, the surgical indication for this challenging procedure is controversial. Thus, this study aimed to evaluate the efficacy of simultaneous HA resection and reconstruction for PHC. Methods: Between January 2002 and January 2018, 13 patients with PHC underwent surgical intervention with simultaneous resection and reconstruction of the HA at Yamaguchi University Hospital (Ube, Japan) and Osaka University Hospital (Suita, Japan). Results: There were 2 cases (15.4%) of 90-day postoperative mortality. Nine patients (69.2%) developed major postoperative complications (Clavien-Dindo classification ≥IIIa). Curative resections (R0) were achieved in 8 cases (61.5%). The median survival time (MST) and 1- and 3-year survival rates after resection (including in-hospital deaths) were 20.9 months and 61.5 and 10.3%, respectively. The MST and 1- and 2-year survival rates of 8 patients who underwent R0 resection were significantly better than those of the other 5 patients (24.2 vs. 10.2 months, 75.0 vs. 40.0%, and 50.0 vs. 0.0%, respectively, p = 0.0228). Conclusions: Simultaneous HA resection and reconstruction is technically possible and may provide long-term survival in selected patients with locally advanced PHC.