Open AccessCoronavirus Disease 2019 (COVID-19): A Haematologist’s Perspective
Author(s) -
Carmen Ka Man Cheung,
Man Fai Law,
Grace Lui,
Sunny H. Wong,
Raymond Wong
Publication year - 2020
Publication title -
acta haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 56
eISSN - 1421-9662
pISSN - 0001-5792
DOI - 10.1159/000510178
Subject(s) - medicine , pandemic , disease , coronavirus , disseminated intravascular coagulation , coronaviridae , covid-19 , hematopoietic stem cell transplantation , immunology , hematology , intensive care medicine , infectious disease (medical specialty)
Coronavirus disease 2019 (COVID-19) is affecting millions of patients worldwide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the family Coronaviridae, with 80% genomic similarities to SARS-CoV. Lymphopenia was commonly seen in infected patients and has a correlation to disease severity. Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. This pandemic has caused disruption in communities and hospital services, as well as straining blood product supply, affecting chemotherapy treatment and haematopoietic stem cell transplantation schedule. In this article, we review the haematological manifestations of the disease and its implication on the management of patients with haematological disorders.
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