Use of Remifentanil for Open in utero Fetal Myelomeningocele Repair Maintains Uterine Relaxation with Reduced Volatile Anesthetic Concentration | Zendy

Benjamin J. Marsh | Zendy; Jina L. Sinskey | Zendy; Elizabeth L. Whitlock | Zendy; Marla B. Ferschl | Zendy; Mark D. Rollins | Zendy

Open Access

Use of Remifentanil for Open in utero Fetal Myelomeningocele Repair Maintains Uterine Relaxation with Reduced Volatile Anesthetic Concentration

Author(s) -

Benjamin J. Marsh,

Jina L. Sinskey,

Elizabeth L. Whitlock,

Marla B. Ferschl,

Mark D. Rollins

Publication year - 2020

Publication title -

fetal diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.976

H-Index - 60

eISSN - 1421-9964

pISSN - 1015-3837

DOI - 10.1159/000509384

Subject(s) - remifentanil , medicine , desflurane , anesthesia , anesthetic , fetal surgery , umbilical artery , fentanyl , sevoflurane , propofol , in utero , surgery , fetus , pregnancy , biology , genetics

Open fetal repair of myelomeningocele (MMC) is an option for prenatally diagnosed spina bifida. Historically, high-dose volatile anesthetic was used for uterine relaxation but is associated with fetal cardiovascular depression. We examined the impact of administering a supplemental remifentanil infusion on the concentration of inhaled anesthetic required for intraoperative uterine relaxation.

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