Open AccessUse of Remifentanil for Open in utero Fetal Myelomeningocele Repair Maintains Uterine Relaxation with Reduced Volatile Anesthetic Concentration
Author(s) -
Benjamin J. Marsh,
Jina L. Sinskey,
Elizabeth L. Whitlock,
Marla B. Ferschl,
Mark D. Rollins
Publication year - 2020
Publication title -
fetal diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 60
eISSN - 1421-9964
pISSN - 1015-3837
DOI - 10.1159/000509384
Subject(s) - remifentanil , medicine , desflurane , anesthesia , anesthetic , fetal surgery , umbilical artery , fentanyl , sevoflurane , propofol , in utero , surgery , fetus , pregnancy , biology , genetics
Open fetal repair of myelomeningocele (MMC) is an option for prenatally diagnosed spina bifida. Historically, high-dose volatile anesthetic was used for uterine relaxation but is associated with fetal cardiovascular depression. We examined the impact of administering a supplemental remifentanil infusion on the concentration of inhaled anesthetic required for intraoperative uterine relaxation.