Open AccessOnce Weekly Application of Urea 40% and Bifonazole 1% Leads to Earlier Nail Removal in Onychomycosis
Author(s) -
Avner Shemer,
Yossi Eshel,
Aditya K. Gupta,
Renata Farhi,
Eckart Haneke,
C. Ralph Daniel,
Kelly A. Foley,
Emma M Quinlan
Publication year - 2020
Publication title -
skin appendage disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 13
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000508926
Subject(s) - bifonazole , medicine , nail (fastener) , urea , surgery , zoology , dermatology , chemistry , antifungal , biology , biochemistry , materials science , metallurgy
Onychomycosis is a chronic nail fungal infection resulting in nail damage and a decreased quality of life. Chemical avulsion of the nail with urea and bifonazole -removes fungally infected debris, increasing antifungal treatment efficacy and penetration. Previous clinical ob-servations describe patients who applied their urea and -bifonazole ointment less frequently, achieving earlier nail removal. In this study, we analyzed the relationship between duration of urea and bifonazole application and time to nail avulsion.