Open AccessEndoscopic Ultrasound-Guided Celiac Plexus Interventions
Author(s) -
Moutinho-Ribeiro Pedro,
Costa-Moreira Pedro,
Caldeira Ana,
Leite Sílvia,
Marques Susana,
Moreira Teresa,
Nunes Nuno,
Bispo Miguel
Publication year - 2020
Publication title -
ge - portuguese journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 9
eISSN - 2387-1954
pISSN - 2341-4545
DOI - 10.1159/000508293
Subject(s) - guidelines
Abdominal pain related to pancreatic disease is often extremely disabling. Endoscopic ultrasound (EUS)-guided celiac plexus block (CPB) is used to control pain associated with chronic pancreatitis. EUS-guided celiac plexus neurolysis (CPN) is typically used to reduce pain associated with pancreatic cancer and can be considered early at the time of diagnosis of inoperable disease. EUS-guided celiac plexus interventions have been shown to be significantly effective in pancreatic pain relief, which is achieved in approximately 70–80% of patients with pancreatic cancer and in 50–60% of those with chronic pancreatitis. Serious complications from CPB and CPN are rare. Most frequent adverse events are diarrhoea, orthostatic hypotension, and a transient increase in abdominal pain. In this article, the Portuguese Group for Ultrasound in Gastroenterology (GRUPUGE) presents an updated perspective of the potential role of EUS-guided celiac plexus interventions, addressing the selection criteria and technical issues of different techniques and analysing recent data on their safety and efficacy.