Open AccessFrontal Fibrosing Alopecia and Autoimmune Disorders in a Hispanic Female
Author(s) -
Jessica Carolina Martínez-Rico,
Jesus ÁncerArellano,
Adrián MartínezMoreno,
Sonia Sofía OcampoGarza,
Sonia ChávezÁlvarez
Publication year - 2020
Publication title -
skin appendage disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 13
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000507557
Subject(s) - vitiligo , medicine , etiology , alopecia areata , dermatology , autoimmune disease , immunology , disease , pathology
Frontal fibrosing alopecia (FFA) is a cicatricial alopecia characterized by hairline recession. Multiple autoimmune pathologies have been reported in patients with FFA. Despite the fact that FFA etiology remains unknown, there has been described an association with autoimmune disorders probably caused by an altered activity of cytotoxic CD8 T lymphocytes. Moreover, other autoimmune pathologies develop TH1 and TH17 response. Genetics could be responsible, in part, for the role of multiple simultaneous autoimmune disorders. Herein, we describe a case of a female patient with vitiligo, lichen sclerosus, and autoimmune hypothyroidism who developed a pruritic band-like recession of the frontal hairline. More research is needed in this area since autoimmune events in these patients may not be a mere coincidence.