Open AccessCreatine Phosphokinase Values during Low Starting Dose Isotretinoin Therapy
Author(s) -
Marco Manfredini,
Vincenzo Bettoli,
Riccardo Forconi,
Lucrezia Pacetti,
Francesca Farnetani,
Monica Corazza,
Giovanni Pellacani
Publication year - 2020
Publication title -
skin appendage disorders
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 13
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000507455
Subject(s) - isotretinoin , medicine , regimen , acne , creatine kinase , incidence (geometry) , dermatology , surgery , physics , optics
The value of creatine phosphokinase (CPK) monitoring during isotretinoin therapy is still a matter of debate because of the rarity of muscular and kidney damage in this setting. The aim of the study was to investigate the incidence of CPK elevation during a low starting dose isotretinoin regimen and to discuss the clinical approach to patients with increased CPK.