
Cutaneous Malignant Melanoma Metastasis to the Pseudophakic Lens Capsule with Associated Granulomatous Intraocular Inflammation
Author(s) -
Hibba Quhill,
Hardeep Singh Mudhar,
Kurt Spiteri Cornish,
I G Rennie
Publication year - 2020
Publication title -
ocular oncology and pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.444
H-Index - 10
eISSN - 2296-4681
pISSN - 2296-4657
DOI - 10.1159/000507052
Subject(s) - medicine , pars plana , choroid , enucleation , vitrectomy , metastasis , pathology , ophthalmology , granulomatous inflammation , melanoma , capsulotomy , inflammation , intraocular lens , surgery , retina , visual acuity , cancer , physics , cancer research , optics
Intraocular cutaneous melanoma metastasis (ICMM) is a rare event, accounting for only 5% of all metastases to the eye and orbit. The vast majority of such metastases primarily affect the choroid and vitreoretinal structures. Only three previous cases of predominant lens structure ICMM have been reported in the literature. Histological examination, in all three past cases, was performed on enucleation specimens of painful blind eyes. We present the first case of ICMM to the lens capsule in a comfortable, seeing, pseudophakic eye. This was histologically confirmed following diagnostic pars plana vitrectomy and capsulotomy, and was found to be associated with background granulomatous intraocular inflammation. The potential causes of the granulomatous inflammation are discussed.