Open AccessCardiac Care of Patients with Cardiac Amyloidosis
Author(s) -
Osnat Itzhaki Ben Zadok,
Ran Kornowski
Publication year - 2020
Publication title -
acta haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 56
eISSN - 1421-9662
pISSN - 0001-5792
DOI - 10.1159/000506919
Subject(s) - amyloidosis , cardiac amyloidosis , medicine , transthyretin , cardiomyopathy , amyloid (mycology) , heart failure , restrictive cardiomyopathy , al amyloidosis , immunoglobulin light chain , cardiology , amyloid fibril , pathology , intensive care medicine , disease , antibody , immunology , amyloid β
Cardiac amyloidosis, the majority of cases of which are due to immunoglobulin light chain amyloidosis (AL) and transthyretin amyloidosis (ATTR), affects different aspects of the heart and cardiovascular system. Amyloid-induced cardiomyopathy, clinically manifesting with heart failure and electrophysiological abnormalities, has distinct characteristics compared to non-amyloid cardiomyopathies. Accordingly, specific management strategies are required. This paper will review the cardiovascular manifestations of patients with cardiac amyloidosis and their suggested treatment strategies, emphasizing the importance of multidisciplinary care.