Open AccessCerebral Hemodynamics Are Not Affected by the Size of the Patent Ductus Arteriosus
Author(s) -
Eun Sun Kim,
Jeffrey R. Kaiser,
Danielle R. Rios,
Renee A. Bornemeier,
Christopher J. Rhee
Publication year - 2020
Publication title -
neonatology
Language(s) - English
Resource type - Journals
eISSN - 1661-7819
pISSN - 1661-7800
DOI - 10.1159/000506835
Subject(s) - ductus arteriosus , medicine , cardiology , cerebral blood flow , hemodynamics , blood pressure , intraventricular hemorrhage , diastole , cerebral autoregulation , gestational age , autoregulation , pregnancy , biology , genetics
Although patent ductus arteriosus (PDA) has been implicated to play a role in the development of cerebral ischemia and intraventricular hemorrhage (IVH) through a cerebral steal phenomenon, there is conflicting data on the impact of PDA size on cerebral blood flow (CBF). Cerebral autoregulation is the brain's innate protective mechanism to maintain constant CBF despite changes in blood pressure, and it is unclear if it is influenced by PDA hemodynamics.