Open AccessLower Oxytocin Levels Are Associated with Lower Bone Mineral Density and Less Favorable Hip Geometry in Hypopituitary Men
Author(s) -
Anna Aulinas,
Francisco J Guarda,
Elaine W. Yu,
Melanie S Haines,
Elisa Asanza,
Lisseth Silva,
Nicholas A. Tritos,
Joseph G. Verbalis,
Karen K. Miller,
Elizabeth A. Lawson
Publication year - 2020
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000506638
Subject(s) - medicine , oxytocin , vasopressin , endocrinology , bone mineral , hypopituitarism , posterior pituitary , diabetes insipidus , hormone , osteoporosis , pituitary gland
Hypopituitary patients are at risk for bone loss. Hypothalamic-posterior pituitary hormones oxytocin and vasopressin are anabolic and catabolic, respectively, to the skeleton. Patients with hypopituitarism may be at risk for oxytocin deficiency. Whether oxytocin and/or vasopressin contribute to impaired bone homeostasis in hypopituitarism is unknown.