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High DHEAS Level in Girls Is Associated with Earlier Pubertal Maturation and Mild Increase in Androgens throughout Puberty without Affecting Postmenarche Ovarian Morphology
Author(s) -
Paulina M. Merino,
Ana Pereira,
Germán Iñíguez,
Camila Corvalán,
Verónica Mericq
Publication year - 2019
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000506632
Subject(s) - adrenarche , menarche , androstenedione , medicine , hyperandrogenism , androgen , endocrinology , testosterone (patch) , polycystic ovary , body mass index , precocious puberty , free androgen index , polycystic ovarian disease , breast development , hormone , obesity , sex hormone binding globulin , insulin resistance
To assess whether the presence of high DHEAS (HD) at 7 years determines different timing, sequence, and rate of pubertal events, and whether it is associated with adrenal and/or ovarian hyperandrogenism and changes in ovarian morphology throughout puberty.

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