Open AccessImportance of Complete Pathology Reporting for Neuroendocrine Carcinoma: WHO Guidelines Are a Good Start but Not Enough
Author(s) -
Wouter T Zandee,
Jan Maarten van der Zwan,
Wouter W. de Herder,
MarieLouise F. van Velthuysen
Publication year - 2020
Publication title -
neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.493
H-Index - 101
eISSN - 1423-0194
pISSN - 0028-3835
DOI - 10.1159/000505920
Subject(s) - medicine , chromogranin a , neuroendocrine carcinoma , immunohistochemistry , grading (engineering) , synaptophysin , pathology , neuroendocrine tumors , gastroenterology , biology , ecology
Neuroendocrine carcinomas (NECs) are diagnosed through a combination of immunohistochemistry (IHC) and morphology according to WHO guidelines. The presence of these crucial components for classification in the pathology report is critical for appropriate understanding of the report especially since terminology and definitions of NEC have been changing a lot lately.