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Coexistence of Pure Red Cell Aplasia and Autoimmune Haemolytic Anaemia Associated with Thymoma
Author(s) -
Wei Wang,
Liyan Chen,
Weiwei Zhao,
Yi Ren,
Lianjie Wang,
Xiaoyun Li,
Yongfang Jiang,
Haiyan Gao
Publication year - 2020
Publication title -
acta haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 56
eISSN - 1421-9662
pISSN - 0001-5792
DOI - 10.1159/000503376
Subject(s) - thymoma , pure red cell aplasia , thymectomy , medicine , immunology , immune system , aplasia , myasthenia gravis , autoimmune disease , disease , pathology , bone marrow
Thymoma is an uncommon neoplasia derived from the epithelial cells of the thymus, which leads to immune dysregulation and is associated with a series of autoimmune diseases. However, the concurrence of these disease entities is rare, and the exact mechanisms of these diseases are still unclear. We have admitted several cases who were diagnosed with thymoma, autoimmune haemolytic anaemia, and pure red cell aplasia. These cases were the first to report the concurrence of these three disorders. After thymectomy, anaemia improved, haemolytic cells decreased, and haemoglobin was normalized.

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