Open AccessGenital Dysplasia and Immunosuppression: Why Organ-Specific Therapy Is Important
Author(s) -
Raphael Sager,
Pascal Frei,
Urs Steiner,
Daniel Fink,
Cornelia Betschart
Publication year - 2019
Publication title -
inflammatory intestinal diseases
Language(s) - English
Resource type - Journals
eISSN - 2296-9403
pISSN - 2296-9365
DOI - 10.1159/000502687
Subject(s) - medicine , immunosuppression , dysplasia , colposcopy , cervical intraepithelial neoplasia , vedolizumab , hpv infection , sex organ , intraepithelial neoplasia , gastroenterology , biopsy , dermatology , gynecology , ulcerative colitis , cervical cancer , disease , cancer , prostate , biology , genetics
Young patients with Crohn's disease (CD) show a high prevalence of human papillomavirus (HPV) which is the main cause of high-grade squamous intraepithelial lesions (HSIL). A major complication for patients undergoing immunocompromising therapy is the development of genital dysplasia.