Open Access“Homomorphic” Tumor Metastases as an Endodiagnostic Clue: A Case Series of Renal-Cell Carcinoma Metastatic to the Stomach
Author(s) -
Simcha Weissman,
Tej I Mehta,
Alex Zhornitskiy,
Rashmi Tondon,
James H. Tabibian
Publication year - 2019
Publication title -
gastrointestinal tumors
Language(s) - English
Resource type - Journals
eISSN - 2296-3766
pISSN - 2296-3774
DOI - 10.1159/000502520
Subject(s) - malignancy , renal cell carcinoma , medicine , stomach , pathology , gastric carcinoma , primary tumor , metastasis , kidney , metastatic carcinoma , carcinoma , cancer
Distinguishing between a primary malignancy and a metastasis can be challenging in some cases. Herein, we describe 2 cases of gastric lesions that were endoscopically sampled and ultimately found to be metastatic from a renal-cell carcinoma. In both cases, the gastric metastases were endoscopically homomorphic to the primary organ (the kidney); i.e., grossly resembling and thus providing an endoscopic clue as to the primary tumor source. We report on the evaluation of obscure metastatic gastric involvement of malignancy and present the concept of homomorphism as a potential diagnostic clue in determining the source of unknown and often unsuspected primary malignancy.