Open AccessRespiratory Sinus Arrhythmia Attenuation via Targeted Lung Denervation in Sheep and Humans
Author(s) -
Arschang Valipour,
Martin L. Mayse,
Alexander D. Peterson,
Philip J. Johnson,
Kristina Rouw,
Sherwin Asadi,
James P. Hummel
Publication year - 2019
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000501623
Subject(s) - medicine , denervation , vagal tone , lung , heart rate variability , respiratory system , cardiology , heart rate , endocrinology , blood pressure
Targeted lung denervation (TLD) is a novel bronchoscopic therapy that disrupts parasympathetic pulmonary nerve input to the lung. Parasympathetic input to the heart originating from the lungs contributes to respiratory sinus arrhythmia (RSA) and disruption of pulmonary nerves via TLD may impact RSA.