Open AccessRhesus D Antigenic Determinants on Residual Red Blood Cells in Apheresis and Buffy Coat Platelet Concentrates
Author(s) -
Louis Thibault,
Marie Joëlle de Grandmont,
Marie-Pierre Cayer,
Nathalie Dussault,
Annie Jacques,
Éric Ducas,
Annie Beauséjour,
A. Lebrun
Publication year - 2019
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000501106
Subject(s) - buffy coat , apheresis , platelet , immunology , antigen , medicine , virology
The level of residual red blood cells (RBCs) in platelet concentrates (PCs) is of interest because of clinical concerns related to alloimmunization to RBC antigens in transfused patients. This work aims at characterizing and quantifying the levels of intact and fragmented RBCs in apheresis (AP-PCs) and buffy coat PCs (BC-PCs) to assess their potential risk for RhD antigen alloimmunization.