Perioperative Hemostatic Management of a Pediatric Patient with Glanzmann Thrombasthenia Undergoing Osteoplastic Craniotomy and Hematoma Removal: A Case Report | Zendy

Sung Min Lee | Zendy; Kyu Nam Kim | Zendy; Soo Yeon Kim | Zendy

Open Access

Perioperative Hemostatic Management of a Pediatric Patient with Glanzmann Thrombasthenia Undergoing Osteoplastic Craniotomy and Hematoma Removal: A Case Report

Author(s) -

Sung Min Lee,

Kyu Nam Kim,

Soo Yeon Kim

Publication year - 2019

Publication title -

acta haematologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.574

H-Index - 56

eISSN - 1421-9662

pISSN - 0001-5792

DOI - 10.1159/000499362

Subject(s) - medicine , thrombasthenia , glanzmann's thrombasthenia , tranexamic acid , hemostasis , surgery , hematoma , craniotomy , platelet , perioperative , recombinant factor viia , anesthesia , von willebrand disease , blood loss , von willebrand factor , platelet aggregation

Glanzmann thrombasthenia is an uncommon hereditary disease that involves an abnormal platelet function leading to complicated hemostatic problems. In situations of anticipated hemorrhage, irradiated apheresed platelets are the first line of treatment. In addition, a combination of recombinant factor VIIa and an antifibrinolytic agent such as tranexamic acid can be utilized to minimize bleeding. Here we are present stable management of a pediatric patient with Glanzmann thrombasthenia admitted for traumatic epidural hematoma removal. Due to the condition of the operation site, some blood loss was unavoidable. However, hemostasis was successfully controlled, and the patient was discharged without additional complications.

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