Open AccessAxitinib-Induced Hypothyroidism as a Predictor of Long-Term Survival in Patients with Metastatic Renal Cell Carcinoma
Author(s) -
Shiro Takada,
Hirokazu Hashishita,
Satoshi Nagamori,
Makoto Endo
Publication year - 2019
Publication title -
urologia internationalis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.771
H-Index - 53
eISSN - 1423-0399
pISSN - 0042-1138
DOI - 10.1159/000499089
Subject(s) - medicine , axitinib , sunitinib , renal cell carcinoma , levothyroxine , thyroid , thyroid carcinoma , hormone , endocrinology , oncology , gastroenterology , urology
The side effects of sunitinib, namely onset of hypertension and hypothyroidism, have been reported to be predictive biomarkers of treatment efficacy. However, the relationship between hypothyroidism and prolongation of survival in treatment with axitinib, a drug similar to sunitinib, has not yet been reported.