Open AccessAlopecia in Autoimmune Blistering Diseases: A Systematic Review of Pathogenesis and Clinical Features of Disease
Author(s) -
Danica Xie,
Aslı Bilgic-Temel,
Nada Abu Alrub,
Dédée F. Murrell
Publication year - 2019
Publication title -
skin appendage disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 13
eISSN - 2296-9195
pISSN - 2296-9160
DOI - 10.1159/000496836
Subject(s) - medicine , dermatology , epidermolysis bullosa acquisita , pemphigoid , pemphigus , autoantibody , disease , dermatitis herpetiformis , bullous pemphigoid , epidermolysis bullosa , autoimmune disease , clinical trial , immunology , pathology , antibody
Autoimmune blistering diseases (AIBD) are characterised by the body's production of autoantibodies against structural proteins in the epidermis and/or the basement membrane on cutaneous and mucosal surfaces. Alopecia is a complication of AIBD that has generally been overlooked in patients with severe blistering diseases because it is regarded as a cosmetic issue. Yet recent research into quality of life tools has found that stigmatisation by appearance plays a significant role in blistering diseases.