Open AccessYoung-Onset Dementia with Lewy Bodies
Author(s) -
Yosuke Aiba,
Ryuji Sakakibara,
Tsuyoshi Ogata,
Ayako Iimura,
Keiichiro Terayama,
Keiko Suzuki,
Shuichi Katsuragawa,
Yuuki Kato,
Fuyuki Tateno,
Hitoshi Terada,
Tsukasa Inaoka,
Tomoya Nakatsuka
Publication year - 2018
Publication title -
case reports in neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 15
ISSN - 1662-680X
DOI - 10.1159/000495748
Subject(s) - medicine , dementia with lewy bodies , rem sleep behavior disorder , dementia , pediatrics , hypersexuality , lewy body , atrophy , psychiatry , disease , parkinson's disease
Young-onset (< 65 years) dementia is a challenging clinical problem. A 61-year-old man visited our clinic because of a 2-year history of mild cognitive impairment of the executive disorder type. He was initially suspected of having young-onset Alzheimer’s disease due to the lack of motor signs or hippocampal atrophy by conventional brain MRI. However, he proved to have anosmia, erectile dysfunction, hypersexuality, constipation, REM sleep behavior disorder, and emotional lability; imaging findings included positive brain perfusion SPECT, nigrosome MRI, DAT scan, and MIBG myocardial scintigraphy. All these clinical imaging features led to the correct diagnosis of young-onset dementia with Lewy bodies (YOD-DLB). It is hoped that this case report will help facilitate a future prospective study to diagnose and follow YOD-DLB patients with the aim of determining appropriate management and care.