Open AccessSyndromic Craniosynostosis: Complexities of Clinical Care
Author(s) -
Justine O’Hara,
Federica Ruggiero,
Louise Wilson,
Greg James,
Graeme E. Glass,
Owase Jeelani,
Juling Ong,
Richard Bowman,
Michelle Wyatt,
Robert D. Evans,
Martin Samuels,
Richard Hayward,
David Dunaway
Publication year - 2019
Publication title -
molecular syndromology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.609
H-Index - 36
eISSN - 1661-8777
pISSN - 1661-8769
DOI - 10.1159/000495739
Subject(s) - craniosynostosis , craniofacial , medicine , multidisciplinary team , presentation (obstetrics) , multidisciplinary approach , craniofacial abnormality , pediatrics , craniosynostoses , craniofacial surgery , synostosis , intensive care medicine , surgery , nursing , social science , psychiatry , sociology
Patients with syndromic craniosynostosis have a molecularly identified genetic cause for the premature closure of their cranial sutures and associated facial and extra-cranial features. Their clinical complexity demands comprehensive management by an extensive multidisciplinary team. This review aims to marry genotypic and phenotypic knowledge with clinical presentation and management of the craniofacial syndromes presenting most frequently to the craniofacial unit at Great Ormond Street Hospital for Children NHS Foundation Trust.