The Role of Intestinal Fatty Acid Binding Proteins in Protecting Cells from Fatty Acid Induced Impairment of Mitochondrial Dynamics and Apoptosis | Zendy

Suparna SarkarBanerjee | Zendy; Sourav Chowdhury | Zendy; Dwipanjan Sanyal | Zendy; Tulika Mitra | Zendy; Sib Sankar Roy | Zendy; Krishnananda Chattopadhyay | Zendy

Open Access

The Role of Intestinal Fatty Acid Binding Proteins in Protecting Cells from Fatty Acid Induced Impairment of Mitochondrial Dynamics and Apoptosis

Author(s) -

Suparna SarkarBanerjee,

Sourav Chowdhury,

Dwipanjan Sanyal,

Tulika Mitra,

Sib Sankar Roy,

Krishnananda Chattopadhyay

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000495672

Subject(s) - microbiology and biotechnology , apoptosis , biology , blot , ectopic expression , mitochondrion , fatty acid , cytochrome c , cell , flow cytometry , biochemistry , gene

The conformation, folding and lipid binding properties of the intestinal fatty acid binding proteins (IFABP) have been extensively investigated. In contrast, the functional aspects of these proteins are not understood and matter of debates. In this study, we aim to address the deleterious effects of FA overload on cellular components, particularly mitochondria; and how IFABP helps in combating this stress by restoring the mitochondrial dynamics.

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