A Unique Case of Primary Extranodal Marginal Zone Lymphoma of the Anal Canal | Zendy

Panagiotis Diamantopoulos | Zendy; Georgios Dryllis | Zendy; Gerasimos Tsourouflis | Zendy; Kyriaki Petevi | Zendy; Georgios Boutsikas | Zendy; Phoebe Rondogianni | Zendy; Dimitrios Boutsis | Zendy; Penelope Korkolopoulou | Zendy; Κωνσταντίνος Κωνσταντόπουλος | Zendy; Maria K. Angelopoulou | Zendy; John Meletis | Zendy; George Kanellis | Zendy; Theodoros P. Vassilakopoulos | Zendy

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A Unique Case of Primary Extranodal Marginal Zone Lymphoma of the Anal Canal

Author(s) -

Panagiotis Diamantopoulos,

Georgios Dryllis,

Gerasimos Tsourouflis,

Kyriaki Petevi,

Georgios Boutsikas,

Phoebe Rondogianni,

Dimitrios Boutsis,

Penelope Korkolopoulou,

Κωνσταντίνος Κωνσταντόπουλος,

Maria K. Angelopoulou,

John Meletis,

George Kanellis,

Theodoros P. Vassilakopoulos

Publication year - 2019

Publication title -

acta haematologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.574

H-Index - 56

eISSN - 1421-9662

pISSN - 0001-5792

DOI - 10.1159/000495601

Subject(s) - marginal zone , malt lymphoma , lymphoma , mucosa associated lymphoid tissue , rectum , lymphatic system , pathology , medicine , gastrointestinal tract , stomach , anal canal , b cell , biology , gastroenterology , immunology , antibody

Marginal zone lymphomas represent approximately 10–12% of all B-cell lymphomas. Extranodal marginal zone lymphomas (EMZL) or mucosa-associated lymphoid tissue (MALT) lymphomas are the most common subtype. Almost half of all MALT lymphomas arise in the gastrointestinal (GI) tract and, while the stomach is the most common site of GI involvement, the small and large intestines can also be involved. Rare cases of MALT lymphoma involving the rectum have been reported; however, to our knowledge, involvement of the anal canal has never been reported in the literature. Here, we describe a unique case of MALT lymphoma of the anal canal. Infectious agents have been implicated in the pathogenesis of MALT lymphomas, possibly through persistent antigenic stimulation of the area; however, in our case no such infection was documented.

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