Open AccessEarly-Life Environmental Factors, IFN-γ Methylation Patterns, and Childhood Allergic Rhinitis
Author(s) -
Youjin Li,
Xiaoqing Rui,
Beiying Ma,
Fan Jiang,
Jie Chen
Publication year - 2019
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000495304
Subject(s) - dna methylation , allergy , medicine , immunology , methylation , confounding , atopy , biology , genetics , dna , gene , gene expression
While early-life risk factors are known to influence the risk of allergies, the biological mechanisms underlying this observation are unclear. The aim of this study was to examine whether DNA methylation in childhood could underlie the association between early-life risk factors and allergic rhinitis (AR).