Open AccessRed Blood Cells Derived from Whole Blood Treated with Riboflavin and UV Light Maintain Adequate Cell Quality through 21 Days of Storage
Author(s) -
Lina Y. Dimberg,
Suzann Doane,
Susan Yonemura,
Heather L. Reddy,
Nick Hovenga,
E Jane Gosney,
Melissa Tran,
Shilo Wilkinson,
Raymond P. Goodrich,
Susanne Marschner
Publication year - 2019
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000495257
Subject(s) - leukoreduction , riboflavin , haemolysis , red blood cell , ultraviolet light , whole blood , autoanalyzer , hemolysis , chemistry , microbiology and biotechnology , biology , medicine , andrology , blood transfusion , food science , immunology , chromatography , photochemistry
The Mirasol system for whole blood (WB) is a non-toxic, non-mutagenic pathogen reduction technology (PRT) that treats WB units with riboflavin (vitamin B 2 ) and ultraviolet (UV) light to alter nucleic acids, thereby reducing pathogen infectivity and inactivating white blood cells. This study evaluates the quality of red blood cells (RBCs) derived from WB treated with the Mirasol system.