Isolated Nail Dystrophy: An Unlikely Presentation of Metastatic Renal Cell Carcinoma | Zendy

Sarah F. McClees | Zendy; J. R. Duncan | Zendy; Roger I. Ceilley | Zendy; Tiffani L. Milless | Zendy; Boni E. Elewski | Zendy

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Isolated Nail Dystrophy: An Unlikely Presentation of Metastatic Renal Cell Carcinoma

Author(s) -

Sarah F. McClees,

J. R. Duncan,

Roger I. Ceilley,

Tiffani L. Milless,

Boni E. Elewski

Publication year - 2018

Publication title -

skin appendage disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.773

H-Index - 13

eISSN - 2296-9195

pISSN - 2296-9160

DOI - 10.1159/000495121

Subject(s) - medicine , malignancy , renal cell carcinoma , metastasis , nail (fastener) , differential diagnosis , cancer , presentation (obstetrics) , lesion , metastatic lesion , pathology , clear cell renal cell carcinoma , dermatology , radiology , materials science , metallurgy

Metastasis of any malignancy to the nail unit is uncommon, and only a handful of cases of subungual renal cell carcinoma (RCC) metastasis have been reported. We describe a case of isolated nail dystrophy that proved to be the presenting symptom of a previously undetected RCC. In a patient presenting with a subungual lesion, tumor metastasis to the nail unit should be included in the clinical differential diagnosis in both oncology patients and previously cancer-free individuals, as a subungual metastasis may be the first indication of a clinically silent visceral malignancy.

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