Open AccessRapidly and Slowly Growing Lineages in Chromosomal Instability-Type Gland-Forming Gastric Carcinomas as Revealed by Multisampling Analysis of DNA Copy-Number Profile
Author(s) -
Tu Thanh Duong,
Diem Thi-Ngoc Vo,
Tadanobu Nakayama,
Kenichi Mukaisho,
Masamichi Bamba,
Trung Sao Nguyen,
Hiroyuki Sugihara
Publication year - 2019
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000494926
Subject(s) - chromosome instability , biology , dna , genome instability , genetics , gene , dna damage , chromosome
To examine whether gastric carcinoma (GC) with chromosomal instability (CIN-type GC), the largest category in the Cancer Genome Atlas classification, consists of a single genetic lineage, we conducted a multisampling analysis of genomic DNA copy-number profile.