Open AccessTacrolimus Suppositories in Therapy-Resistant Ulcerative Proctitis
Author(s) -
Simon U. Jaeger,
Thomas Klag,
Katharina Hoeger,
Siegfried Klumpp,
Monica Escher,
Nisar P. Malek,
Eduard F. Stange,
Jan Wehkamp
Publication year - 2018
Publication title -
inflammatory intestinal diseases
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2296-9403
pISSN - 2296-9365
DOI - 10.1159/000493979
Subject(s) - medicine , ulcerative colitis , tacrolimus , mesalazine , gastroenterology , proctitis , concomitant , refractory (planetary science) , urology , transplantation , physics , disease , astrobiology
Ulcerative proctitis may often be managed with topical salicylates or steroids alone, but in some patients, symptoms are persistent and severe. We analyzed the efficacy of tacrolimus suppositories in patients who had proven refractory to combined topical and systemic treatment.