Open AccessImpact of Modern Drug Therapy on Surgery: Ulcerative Colitis
Author(s) -
Florian Kuehn,
Richard A. Hodin
Publication year - 2018
Publication title -
visceral medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.598
H-Index - 17
eISSN - 2297-475X
pISSN - 2297-4725
DOI - 10.1159/000493492
Subject(s) - medicine , ulcerative colitis , drug , refractory (planetary science) , intervention (counseling) , surgery , pharmacotherapy , general surgery , disease , pharmacology , physics , psychiatry , astrobiology
The primary treatment of ulcerative colitis (UC) is conservative, and substantial therapeutic progress has been made in the past few decades. Meanwhile, biologicals have become a mainstay in the treatment for steroid-refractory UC. Despite further development of drug therapy and an increased time span to operation, a significant proportion of patients with UC require surgical intervention. Surgical intervention needs to be carried out in medically refractory cases, imminent or malignant transformation, or complications. This article discusses the impact of modern drug therapy on surgery for UC.