Progression Potential of Ductal Carcinoma in situ Assessed by Genomic Copy Number Profiling | Zendy

Mina Kitamura | Zendy; Takahisa Nakayama | Zendy; Kenichi Mukaisho | Zendy; Tsuyoshi Mori | Zendy; Tomoko Umeda | Zendy; Suzuko Moritani | Zendy; Ryoji Kushima | Zendy; Masaji Tani | Zendy; Hiroyuki Sugihara | Zendy

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Progression Potential of Ductal Carcinoma in situ Assessed by Genomic Copy Number Profiling

Author(s) -

Mina Kitamura,

Takahisa Nakayama,

Kenichi Mukaisho,

Tsuyoshi Mori,

Tomoko Umeda,

Suzuko Moritani,

Ryoji Kushima,

Masaji Tani,

Hiroyuki Sugihara

Publication year - 2018

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000492833

Subject(s) - copy number variation , ductal carcinoma , biology , comparative genomic hybridization , profiling (computer programming) , computational biology , copy number analysis , oncology , pathology , medicine , genome , genetics , cancer , breast cancer , gene , computer science , operating system

Ductal carcinoma in situ (DCIS) of the breast is heterogeneous in terms of the risk of progression to invasive ductal carcinoma (IDC). To treat DCIS appropriately for its progression risk, we classified individual DCIS by its profile of genomic changes into 2 groups and correlated them with clinicopathological progression factors.

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