Open AccessGinsenoside Rg1 Prevents Chronic Stress-Induced Depression-Like Behaviors and Neuronal Structural Plasticity in Rats
Author(s) -
Hao Yu,
Chunhua Fan,
Lejin Yang,
Shu Yu,
Qianqian Song,
Peng Wang,
Xinrui Mao
Publication year - 2018
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000492684
Subject(s) - creb , neuroprotection , neurotrophic factors , chronic stress , antidepressant , basolateral amygdala , neuroplasticity , neuroscience , ginsenoside , hippocampus , synaptic plasticity , endocrinology , medicine , pharmacology , chemistry , psychology , amygdala , transcription factor , receptor , ginseng , pathology , biochemistry , alternative medicine , gene
Ginsenoside Rg1 has been demonstrated to exhibit neuroprotective effects in various studies. This study aimed to investigate the neuronal mechanisms underlying the neuroprotective and antidepressant-like effects of ginsenoside Rg1 in a rat model of depression.