Open AccessEffect of Thyroid Hormones on Neurons and Neurodevelopment
Author(s) -
Giovanni Prezioso,
Cosimo Giannini,
Francesco Chiarelli
Publication year - 2018
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000492129
Subject(s) - hormone , thyroid hormones , thyroid , central nervous system , medicine , brain development , fetus , affect (linguistics) , congenital hypothyroidism , physiology , endocrinology , pregnancy , neuroscience , biology , psychology , genetics , communication
This review focuses on the current knowledge of the effects of thyroid hormones on central nervous system differentiation and development in animals and the human fetal brain. The outcomes of children with congenital hypothyroidism and of newborns with hypothyroid pregnant mothers are emphasized, focusing on how therapies could affect and especially improve the outcomes.