Open AccessDeficit in Memory Is Associated with Paradoxical Regulation of Magnesium and Manganese in Isolated Male Rats
Author(s) -
Hamidreza Famitafreshi,
Morteza Karimian
Publication year - 2018
Publication title -
annals of neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.545
H-Index - 19
eISSN - 0976-3260
pISSN - 0972-7531
DOI - 10.1159/000491918
Subject(s) - manganese , magnesium , medicine , physiology , chemistry , organic chemistry
Magnesium (Mg) and manganese (Mn) play an important role in brain development and glutathione, the master antioxidant in the brain, is necessary for the cognitive function. This study is aimed at determining the effect of magnesium and manganese concentrations in hippocampus and prefrontal cortex on the glutathione function. The reduction in glutathione leads to memory impairment in -Y-maze in the isolation period.