Open AccessA Sequential Study of Age-Related Lipofuscin Accumulation in Hippocampus and Striate Cortex of Rats
Author(s) -
Sarika Singh Kushwaha,
Nisha Patro,
Nisha Patro
Publication year - 2018
Publication title -
annals of neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.545
H-Index - 19
eISSN - 0976-3260
pISSN - 0972-7531
DOI - 10.1159/000490908
Subject(s) - lipofuscin , microglia , hippocampus , neun , cortex (anatomy) , biology , cresyl violet , neurodegeneration , neuroscience , microbiology and biotechnology , pathology , immunohistochemistry , staining , medicine , biochemistry , immunology , inflammation , genetics , disease
The age-pigment, lipofuscin that accumulates in cells intrinsically and progressively with age is considered as the hallmark of aging. This accumulation is more prominent in post-mitotic cells like neurons and also appears in glia.