Open AccessEvaluation of the Role of <b><i>BRAF</i></b>V600E Somatic Mutation on Papillary Thyroid Cancer Disease Persistence: A Prospective Study
Author(s) -
Luca Damiani,
Sabrina Lupo,
Roberta Rossi,
Stefano Bruni,
Mirco Bartolomei,
Stefano Panareo,
Paola Franceschetti,
Paolo Carcoforo,
Giovanni Lanza,
Stefano Pelucchi,
Ettore Degli Uberti,
Maria Chiara Zatelli
Publication year - 2018
Publication title -
european thyroid journal
Language(s) - English
Resource type - Journals
eISSN - 2235-0802
pISSN - 2235-0640
DOI - 10.1159/000490699
Subject(s) - medicine , papillary thyroid cancer , germline mutation , somatic cell , prospective cohort study , mutation , disease , thyroidectomy , thyroglobulin , gastroenterology , thyroid cancer , thyroid , pathology , oncology , gene , genetics , biology
BRAF V600E (c.1799T>A) somatic mutation evaluation in fine needle aspiration biopsies (FNAB) is a powerful diagnostic tool in the settings of papillary thyroid cancer (PTC). However, its prognostic value is still a matter of great debate and has been addressed mostly in retrospective studies.