Open AccessUltraviolet Inactivation of Chikungunya Virus
Author(s) -
Asha Maria Mathew,
Amol Baburao Mun,
Anukumar Balakrishnan
Publication year - 2018
Publication title -
intervirology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000490567
Subject(s) - antigenicity , chikungunya , virology , virus , porcine parvovirus , biology , alphavirus , microbiology and biotechnology , chemistry , antigen , immunology
Chikungunya virus (CHIKV) is a rapidly emerging arbovirus causing millions of infections in more than 40 countries. CHIKV is typically a biosafety level 3 pathogen in many countries and handling of CHIKV requires a high standard of laboratory safety settings. Many studies require the whole virus to be handled in a biosafety level 2 setting. A potential solution for managing this problem is pathogen inactivation without affecting its antigenicity. In the present study, we attempted to inactivate CHIKV by ultraviolet (UV) irradiation.