Open AccessPredicting Lung Function Following Lobectomy: A New Method to Adjust for Inherent Selection Bias
Author(s) -
Narda Ontiveros,
David Eapen-John,
Natasha Osorio,
Juhee Song,
Liang Li,
Ajay Sheshadri,
Xin Tiang,
Natasha Ghosh,
Ara A. Vaporciyan,
Arlene M. Correa,
Garrett L. Walsh,
Horiana B. Grosu,
David Ost
Publication year - 2018
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000490258
Subject(s) - medicine , dlco , selection bias , lung function , pulmonary function testing , bivariate analysis , statistics , surgery , diffusing capacity , lung , mathematics , pathology
Predictions that overestimate post-lobectomy lung function are more likely than underestimates to lead to lobectomy. Studies of post-lobectomy lung function have included only surgical patients, so overestimates are overrepresented. This selection bias has led to incorrect estimates of prediction bias, which has led to inaccurate threshold values for determining lobectomy eligibility.