Raddeanin a Suppresses Glioblastoma Growth by Inducing ROS Generation and Subsequent JNK Activation to Promote Cell Apoptosis | Zendy

Fei Peng | Zendy; Xiaoxiong Wang | Zendy; Mengting Shu | Zendy; Mingfei Yang | Zendy; Ligang Wang | Zendy; Zhongrui Ouyang | Zendy; Chen Shen | Zendy; Xu Hou | Zendy; Boyan Zhao | Zendy; XinZhuang Wang | Zendy; Linda Wei Zhang | Zendy; Yaohua Liu | Zendy; Shiguang Zhao | Zendy

Open Access

Raddeanin a Suppresses Glioblastoma Growth by Inducing ROS Generation and Subsequent JNK Activation to Promote Cell Apoptosis

Author(s) -

Fei Peng,

Xiaoxiong Wang,

Mengting Shu,

Mingfei Yang,

Ligang Wang,

Zhongrui Ouyang,

Chen Shen,

Xu Hou,

Boyan Zhao,

XinZhuang Wang,

Linda Wei Zhang,

Yaohua Liu,

Shiguang Zhao

Publication year - 2018

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000490187

Subject(s) - apoptosis , microbiology and biotechnology , cell growth , chemistry , glioblastoma , cancer research , reactive oxygen species , biology , biochemistry

Raddeanin A (RA), an active pharmacological ingredient from Anemone raddeana Regel, plays an important role in tumor suppression. In this study, we assessed the potentially therapeutic effect of RA on glioblastoma and its underlying mechanisms.

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